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Review
. 2010 Apr 7;11(4):268-72.
doi: 10.1016/j.cmet.2010.03.007.

The changed metabolic world with human brown adipose tissue: therapeutic visions

Jan Nedergaard  1 , Barbara Cannon
Affiliations
Free article
Review

The changed metabolic world with human brown adipose tissue: therapeutic visions

Jan Nedergaard et al. Cell Metab. .
Free article

Abstract

That adult humans possess active brown adipose tissue potentially leads to a paradigm shift in the understanding of human metabolism and of obesity. Adaptive adrenergic thermogenesis in humans represents brown adipose tissue activity, the absence of which may contribute to middle-age obesity.

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