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. 2010 Jun 1;21(11):1783-7.
doi: 10.1091/mbc.e09-07-0589. Epub 2010 Apr 7.

The adipose-derived stem cell: looking back and looking ahead

Patricia A Zuk  1
Affiliations

The adipose-derived stem cell: looking back and looking ahead

Patricia A Zuk. Mol Biol Cell. .

Abstract

In 2002, researchers at UCLA published a manuscript in Molecular Biology of the Cell describing a novel adult stem cell population isolated from adipose tissue-the adipose-derived stem cell (ASC). Since that time, the ASC has gone on to be one of the most popular adult stem cell populations currently being used in the stem cell field. With multilineage mesodermal potential and possible ectodermal and endodermal potentials also, the ASC could conceivably be an alternate to pluripotent ES cells in both the lab and in the clinic. In this retrospective article, a historical perspective on the ASC is given together with exciting new applications for the stem cell being considered today.

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References

    1. Ashjian P. H., Elbarbary A. S., Edmonds B., DeUgarte D. A., Zhu M., Zuk P. A., Lorenz H. P., Benhaim P., Hedrick M. H. In vitro differentiation of human processed lipoaspirate cells into early neural progenitors. Plast. Reconstr. Surg. 2003;111:1922–1931. - PubMed
    1. Bacou F., el Andalousi R. B., Daussin P. A., Micallef J. P., Levin J. M., Chammas M., Casteilla L., Reyne Y., Nouguès J. Transplantation of adipose tissue-derived stromal cells increases mass and functional capacity of damaged skeletal muscle. Cell Transplant. 2004;13:103–111. - PubMed
    1. Banas A., Teratani T., Yamamoto Y., Tokuhara M., Takeshita F., Quinn G., Okochi H., Ochiya T. Adipose tissue-derived mesenchymal stem cells as a source of human hepatocytes. Hepatology. 2007;46:219–228. - PubMed
    1. Becker A. J., McCulloch E. A., Till J. E. Cytological demonstration of the clonal nature of spleen colonies derived from transplanted mouse marrow cells. Nature. 1963;197:452–454. - PubMed
    1. Broxmeyer H. E., Gluckman E., Auerbach A., Douglas G. W., Friedman H., Cooper S., Hangoc G., Kurtzberg J., Bard J., Boyse E. A. Human umbilical cord blood: a clinically useful source of transplantable hematopoietic stem/progenitor cells. Int. J. Cell Cloning. 1990;8(suppl 1):76–89. discussion 89–91. - PubMed

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