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. 2010 Apr;7(4):191-3.
doi: 10.1038/nrgastro.2010.40.

Hepatitis: Treatment of chronic hepatitis C-how much interferon is enough?

Peter Ferenci  1
Affiliations

Hepatitis: Treatment of chronic hepatitis C-how much interferon is enough?

Peter Ferenci. Nat Rev Gastroenterol Hepatol. 2010 Apr.

Abstract

A multicenter, randomized, controlled trial of 610 patients with chronic hepatitis c infected with hcv genotype 1 or 4 compared 48 weeks of standard of care therapy (PEG-IFN and ribavirin) with 12 weeks of induction therapy with high-dose PEG-IFN followed by 36 weeks of standard of care treatment. High-dose PEG-IFN induction therapy did not enhance early or sustained virologic response rates compared with standard of care therapy.

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