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Case Reports
. 2010 May;51(3):460-2.
doi: 10.3349/ymj.2010.51.3.460.

A case of type B lactic acidosis in acute leukemia

Hae Seung Lee  1 , Hyun Jung Kim, Soojeong Choi, Chan Kyu Kim, Nam Su Lee, Kyu Taek Lee, Jong Ho Won, Hee Sook Park, Dae Sik Hong
Affiliations
Case Reports

A case of type B lactic acidosis in acute leukemia

Hae Seung Lee et al. Yonsei Med J. 2010 May.

Abstract

Type B lactic acidosis is a rare condition in patients with solid tumors or hematological malignancies. Although there have been several theories to explain its mechanism, the exact cause of lactic acidosis remains to be discovered. Lactic acidosis is usually related to increased tumor burden in patients with malignancy. We experienced a case of lactic acidosis in a 39-year-old man who visited an emergency room because of dyspnea, and the cause of lactic acidosis turned out to be recurrent acute leukemia. Chemotherapy relieved the degree of lactic acidosis initially, but as the disease progressed, lactic acidosis became aggravated. Type B lactic acidosis can be a clinical presentation of acute exacerbation of acute leukemia.

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Conflict of interest statement

The authors have no financial conflicts of interest.

Figures

Fig. 1
Fig. 1
Change of blood lactic acid level after chemotherapy. Blood lactic acid level decreased as the patient responded to chemotherapy.
See this image and copyright information in PMC

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