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. 2010 Apr 9:5:23.
doi: 10.1186/1749-8090-5-23.

Outcome of open and endovascular repair in acute type B aortic dissection: a retrospective and observational study

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Outcome of open and endovascular repair in acute type B aortic dissection: a retrospective and observational study

Pasquale Mastroroberto et al. J Cardiothorac Surg. .

Abstract

Background: The aim of the study was to analyze surgical and endovascular results in the treatment of acute type B aortic dissection (B AAD).

Methods: Retrospective and observational analysis with patient inclusion between January 2001-December 2008 and follow-up ranged from 2 to 96 months (median = 47.2) was performed. Out of 51 consecutive patients with B AAD, 11 (21.6%) had to undergo open surgery (OS) and 13 (25.5%) endovascular treatment (TEVAR).

Results: There was a significantly difference in early mortality in the TEVAR group (0/13,0%) vs OS group (4/11,36.4%, P < 0.05) and in the incidence of paraplegia/paraparesis (OS 2,28.6% vs TEVAR 1,7.7%, P < 0.05), renal failure (OS 3, 42.8% vs TEVAR 1, 7.7%, P < 0.05), respiratory failure (OS 2,28.6% vs TEVAR 1,7.7%, P < 0.05) and cerebrovascular accident (OS 1,14.3% vs TEVAR 0,0%, P < 0.05). The late mortality at a follow-up was 30.8% (4/13) in the TEVAR group and 42.8% (3/7) in the OS group, respectively (P = not significant). The cumulative survival rate after 1, 3 and 8 years was 93%, 84%, and 69% in the TEVAR group and 86%, 71% and 57% in the OS group, respectively. Endoleaks were diagnosed in 2/13 endovascular patients (15.4%).

Conclusions: TEVAR group had a significantly reduction in early mortality and postoperative complications. No significant differences were found in terms of cumulative survival at follow-up. On this basis TEVAR could be considered an option in the treatment of these complex cases with all proper reservation especially related to the small sample sizes examined.

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Figures

Figure 1
Figure 1
Comparative survival analysis of OS (dashed line) and TEVAR (solid line) groups by Kaplan-Meier method.

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References

    1. Greenberg R, Khwaja J, Haulon S, Fulton G. Aortic dissections: new perspectives and treatment paradigms. Eur J Vasc Endovasc Surg. 2003;26:579–86. doi: 10.1016/S1078-5884(03)00415-5. - DOI - PubMed
    1. Marui A, Mochizuki T, Mitsui N, Koyama T, Kimura F, Horibe M. Toward the best treatment for uncomplicated patients with type B acute aortic dissection: a consideration for sound surgical indication. Circulation. 1999;100:275–80. - PubMed
    1. Miller DC, Mitchell RS, Oyer PE, Stinson EB, Jamieson SW, Shumway NE. Independent determinants of operative mortality for patients with aortic dissections. Circulation. 1984;70:153–640. - PubMed
    1. Mohindra PK, Rivera V. A prospective randomized study of cerebrospinal fluid drainage to prevent paraplegia after high-risk surgery on the thoracoabdominal aorta. J Vasc Surg. 1991;13:36–45. doi: 10.1067/mva.1991.25385. [discussion 45-6] - DOI - PubMed
    1. Hsu RB, Ho YL, Chen RJ, Wang SS, Lin FY, Chu SH. Outcome of medical and surgical treatment in patients with acute type B aortic dissection. Ann Thorac Surg. 2005;79:790–40. doi: 10.1016/j.athoracsur.2004.07.061. - DOI - PubMed

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