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Comment
. 2010 Apr 9;86(4):650-2; author reply 652-3.
doi: 10.1016/j.ajhg.2009.12.019.

The LCR at the IKBKG locus is prone to recombine

Francesca Fusco, Michele D'Urso, Maria Giuseppina Miano, Matilde Valeria Ursini
Comment

The LCR at the IKBKG locus is prone to recombine

Francesca Fusco et al. Am J Hum Genet. .
No abstract available

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Figures

Figure 1
Figure 1
An Example of NAHR between L1 and L2 Causing a Pathological Allele Is Reported: The Case Represents the IKBKG Locus in an IP Family The unaffected mother (I:2) carrying the exon4_10 deletion in the IKBKGP pseudogene is reported. The IP patient (II:1) carrying the pathogenic deletion in the gene (exon4_10 deletion) is reported. The misalignment between the two LCRs, L1 and L2, produces the intrachromosomal recombination transferring the exon4_10 del deletion (ΔExon4_10) from the pseudogene to the gene in the recombinant allele.
See this image and copyright information in PMC

Comment on

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