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. 1991 Jun;11(6):3384-9.
doi: 10.1128/mcb.11.6.3384-3389.1991.

Cell cycle-specific expression and nuclear binding of DNA polymerase alpha

T Stokke  1 , B Erikstein, H Holte, S Funderud, H B Steen
Affiliations

Cell cycle-specific expression and nuclear binding of DNA polymerase alpha

T Stokke et al. Mol Cell Biol. 1991 Jun.

Abstract

The expression and distribution of DNA polymerase alpha was measured by cytometry and confocal laser scanning microscopy. Expression was proportional to DNA content in proliferating cells, while only S-phase cells retained DNA polymerase alpha after detergent extraction. Nuclear DNA polymerase alpha binding may be one of the key events of S-phase entry.

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