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Comment
. 2010 Apr 9;38(1):1-2.
doi: 10.1016/j.molcel.2010.03.011.

King of the castle: competition between repressors and activators on the Mcm1 platform

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King of the castle: competition between repressors and activators on the Mcm1 platform

Janet Leatherwood et al. Mol Cell. .
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Abstract

Darieva and coworkers (Darieva et al., 2010) have shown that the repressor Yox1 and the activator Fkh2-Ndd1 associate with opposite sides of the dimeric Mcm1 transcription factor but nevertheless compete for binding; the outcome determines expression of late mitotic genes in yeast.

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