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Comment
. 2010 Apr 13;17(4):311-2.
doi: 10.1016/j.ccr.2010.03.013.

Prostate cancer: beta control your hormones

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Prostate cancer: beta control your hormones

Massimo Loda et al. Cancer Cell. .
Free article

Abstract

Differentiation status influences the prognosis for localized prostate cancer. In this issue of Cancer Cell, Mak and coworkers describe a signaling pathway involving estrogen receptor beta (ERbeta) that governs whether prostate carcinoma cells maintain an epithelial phenotype or undergo epithelial-mesenchymal transition, suggesting that ERbeta would have prognostic or therapeutic value.

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