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Review
. 2010 Feb 4;11(2):622-46.
doi: 10.3390/ijms11020622.

Biological activities of polyphenols from grapes

En-Qin Xia  1 , Gui-Fang Deng, Ya-Jun Guo, Hua-Bin Li
Affiliations
Review

Biological activities of polyphenols from grapes

En-Qin Xia et al. Int J Mol Sci. .

Abstract

The dietary consumption of grape and its products is associated with a lower incidence of degenerative diseases such as cardiovascular disease and certain types of cancers. Most recent interest has focused on the bioactive phenolic compounds in grape. Anthocyanins, flavanols, flavonols and resveratrol are the most important grape polyphenols because they possess many biological activities, such as antioxidant, cardioprotective, anticancer, anti-inflammation, antiaging and antimicrobial properties. This review summarizes current knowledge on the bioactivities of grape phenolics. The extraction, isolation and identification methods of polyphenols from grape as well as their bioavailability and potential toxicity also are included.

Keywords: anti-inflammation activity; anticancer activity; antimicrobial effect; antioxidant activity; bioactivity; cardioprotective action; grape; polyphenol.

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Figures

Figure 1.
Figure 1.
The chemical structures of some phenolic compounds from grapes.
See this image and copyright information in PMC

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