Review
doi: 10.1007/978-1-60761-657-3_4.
Progress in siRNA delivery using multifunctional nanoparticles
Affiliations
- PMID: 20387142
- DOI: 10.1007/978-1-60761-657-3_4
Item in Clipboard
Review
Progress in siRNA delivery using multifunctional nanoparticles
Methods Mol Biol.
2010.
Abstract
Nanoparticles made from synthetic polymers have been developed to deliver small interfering RNA (siRNA). For successful siRNA delivery, these nanoparticles need to efficiently encapsulate siRNA, actively target sites of interest, and release siRNA intracellularly. This chapter reviews recent progress using a multifunctional approach to design and engineer polymeric nanoparticles for siRNA delivery.
Similar articles
-
Cationic drug-derived nanoparticles for multifunctional delivery of anticancer siRNA.Biomaterials. 2011 Dec;32(36):9785-95. doi: 10.1016/j.biomaterials.2011.09.017. Epub 2011 Sep 19. Biomaterials. 2011. PMID: 21937102
-
Efficient siRNA delivery to mammalian cells using layered double hydroxide nanoparticles.Biomaterials. 2010 Mar;31(7):1821-9. doi: 10.1016/j.biomaterials.2009.10.058. Epub 2009 Nov 17. Biomaterials. 2010. PMID: 19922997
-
Polymers for siRNA delivery: inspired by viruses to be targeted, dynamic, and precise.Acc Chem Res. 2012 Jul 17;45(7):1005-13. doi: 10.1021/ar2002232. Epub 2011 Dec 22. Acc Chem Res. 2012. PMID: 22191535
-
Advances in synthetic siRNA delivery.Discov Med. 2010 May;9(48):418-30. Discov Med. 2010. PMID: 20515610 Review.
-
Smart siRNA delivery systems based on polymeric nanoassemblies and nanoparticles.Nanomedicine (Lond). 2010 Sep;5(7):1089-102. doi: 10.2217/nnm.10.76. Nanomedicine (Lond). 2010. PMID: 20874023 Review.
Cited by
-
Microfluidics Technology for the Design and Formulation of Nanomedicines.Nanomaterials (Basel). 2021 Dec 18;11(12):3440. doi: 10.3390/nano11123440. Nanomaterials (Basel). 2021. PMID: 34947789 Free PMC article. Review.
-
Nanoparticle-mediated systemic delivery of siRNA for treatment of cancers and viral infections.Theranostics. 2014 Jun 11;4(9):872-92. doi: 10.7150/thno.9404. eCollection 2014. Theranostics. 2014. PMID: 25057313 Free PMC article. Review.
-
Targeted Sterically Stabilized Phospholipid siRNA Nanomedicine for Hepatic and Renal Fibrosis.Nanomaterials (Basel). 2016 Jan 5;6(1):8. doi: 10.3390/nano6010008. Nanomaterials (Basel). 2016. PMID: 28344266 Free PMC article.
-
Self-Amplifying Replicon RNA Vaccine Delivery to Dendritic Cells by Synthetic Nanoparticles.Vaccines (Basel). 2014 Oct 16;2(4):735-54. doi: 10.3390/vaccines2040735. Vaccines (Basel). 2014. PMID: 26344889 Free PMC article. Review.
-
Protein and oligonucleotide delivery systems for vaginal microbicides against viral STIs.Cell Mol Life Sci. 2015 Feb;72(3):469-503. doi: 10.1007/s00018-014-1756-3. Epub 2014 Oct 17. Cell Mol Life Sci. 2015. PMID: 25323132 Free PMC article. Review.
Publication types
MeSH terms
Substances
Grants and funding
LinkOut - more resources
Full Text Sources
Other Literature Sources
