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. 1991 Mar;35(3):582-3.
doi: 10.1128/AAC.35.3.582.

In vitro synergy studies with Clostridium difficile

A E Bacon  1 , S McGrath, R Fekety, W J Holloway
Affiliations

In vitro synergy studies with Clostridium difficile

A E Bacon et al. Antimicrob Agents Chemother. 1991 Mar.

Abstract

Agar dilution anaerobic susceptibility studies using rifampin, vancomycin, metronidazole, and bacitracin individually and in combination were performed with Clostridium difficile. Fifty-five strains of C. difficile were studied. Eighty-five percent of strains tested (29 of 34) were synergistically inhibited by the combination of bacitracin and rifampin (fractional inhibitory concentration, less than or equal to 0.50).

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