Apoptosis: conserved roles for integrins in clearance
- PMID: 20392425
- DOI: 10.1016/j.cub.2010.02.043
Apoptosis: conserved roles for integrins in clearance
Abstract
A recent study shows that one of the two known Caenorhabditis elegans homologs of the mammalian integrin alpha subunit plays an essential role in the clearance of apoptotic cells - efferocytosis - during nematode development. These new findings reveal that integrins have evolutionarily conserved functions in efferocytosis in metazoans.
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