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Review
. 2010 Jul;126(1):3-13; quiz 14-5.
doi: 10.1016/j.jaci.2010.01.055. Epub 2010 Apr 14.

Organ-specific eosinophilic disorders of the skin, lung, and gastrointestinal tract

Dagmar Simon  1 , Andrew Wardlaw, Marc E Rothenberg
Affiliations
Review

Organ-specific eosinophilic disorders of the skin, lung, and gastrointestinal tract

Dagmar Simon et al. J Allergy Clin Immunol. 2010 Jul.

Abstract

Eosinophils are multifunctional leukocytes that increase in various tissues in patients with a variety of disorders. Locally, they can be involved in the initiation and propagation of diverse inflammatory responses. In this review the clinical association of eosinophils with diseases of the skin, lung, and gastrointestinal tract is summarized. An approach to determining the causal role of eosinophils in these diseases is presented. Recent findings concerning molecular diagnosis, cause, and treatment are discussed.

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