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Case Reports
. 2010 Jun;48(6):2298-300.
doi: 10.1128/JCM.00418-10. Epub 2010 Apr 14.

Cardiac tamponade and heart failure due to myopericarditis as a presentation of infection with the pandemic H1N1 2009 influenza A virus

Simona Puzelli  1 , Franco M Buonaguro, Marzia Facchini, Annapina Palmieri, Laura Calzoletti, Maria A De Marco, Pasquale Arace, Enrico de Campora, Ciro Esposito, Antonio Cassone, Giovanni Rezza, Isabella Donatelli; Surveillance Group for Pandemic H1N1 2009 Influenza Virus in Italy; Campania H1N1 Task Force
Collaborators, Affiliations
Case Reports

Cardiac tamponade and heart failure due to myopericarditis as a presentation of infection with the pandemic H1N1 2009 influenza A virus

Simona Puzelli et al. J Clin Microbiol. 2010 Jun.

Abstract

We describe a fatal case of myopericarditis presenting with cardiac tamponade in a previously healthy 11-year-old child. Pandemic H1N1 2009 influenza A virus sequences were identified in throat and myocardial tissues and pericardial fluid, suggesting damage of myocardial cells directly caused by the virus.

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Figures

FIG. 1.
FIG. 1.
Myocardium sample showing moderate myocarditis and the presence of histiocyte infiltration and focal necrosis. The sample was stained with hematoxylin and eosin. Original magnification, ×250.
FIG. 2.
FIG. 2.
Cluster of histiocytic cells (CD68 positive) in the neighborhood of damaged myocytes. Cells were stained with peroxidase. Original magnification, ×250.
See this image and copyright information in PMC

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