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. 2010 Apr 15;464(7291):993-8.
doi: 10.1038/nature08987.

International network of cancer genome projects

International Cancer Genome Consortium; Thomas J Hudson, Warwick Anderson, Axel Artez, Anna D Barker, Cindy Bell, Rosa R Bernabé, M K Bhan, Fabien Calvo, Iiro Eerola, Daniela S Gerhard, Alan Guttmacher, Mark Guyer, Fiona M Hemsley, Jennifer L Jennings, David Kerr, Peter Klatt, Patrik Kolar, Jun Kusada, David P Lane, Frank Laplace, Lu Youyong, Gerd Nettekoven, Brad Ozenberger, Jane Peterson, T S Rao, Jacques Remacle, Alan J Schafer, Tatsuhiro Shibata, Michael R Stratton, Joseph G Vockley, Koichi Watanabe, Huanming Yang, Matthew M F Yuen, Bartha M Knoppers, Martin Bobrow, Anne Cambon-Thomsen, Lynn G Dressler, Stephanie O M Dyke, Yann Joly, Kazuto Kato, Karen L Kennedy, Pilar Nicolás, Michael J Parker, Emmanuelle Rial-Sebbag, Carlos M Romeo-Casabona, Kenna M Shaw, Susan Wallace, Georgia L Wiesner, Nikolajs Zeps, Peter Lichter, Andrew V Biankin, Christian Chabannon, Lynda Chin, Bruno Clément, Enrique de Alava, Françoise Degos, Martin L Ferguson, Peter Geary, D Neil Hayes, Thomas J Hudson, Amber L Johns, Arek Kasprzyk, Hidewaki Nakagawa, Robert Penny, Miguel A Piris, Rajiv Sarin, Aldo Scarpa, Tatsuhiro Shibata, Marc van de Vijver, P Andrew Futreal, Hiroyuki Aburatani, Mónica Bayés, David D L Botwell, Peter J Campbell, Xavier Estivill, Daniela S Gerhard, Sean M Grimmond, Ivo Gut, Martin Hirst, Carlos López-Otín, Partha Majumder, Marco Marra, John D McPherson, Hidewaki Nakagawa, Zemin Ning, Xose S Puente, Yijun Ruan, Tatsuhiro Shibata, Michael R Stratton, Hendrik G Stunnenberg, Harold Swerdlow, Victor E Velculescu, Richard K Wilson, Hong H Xue, Liu Yang, Paul T Spellman, Gary D Bader, Paul C Boutros, Peter J Campbell, Paul Flicek, Gad Getz, Roderic Guigó, Guangwu Guo, David Haussler, Simon Heath, Tim J Hubbard, Tao Jiang, Steven M Jones, Qibin Li, Nuria López-Bigas, Ruibang Luo, Lakshmi Muthuswamy, B F Francis Ouellette, John V Pearson, Xose S Puente, Victor Quesada, Benjamin J Raphael, Chris Sander, Tatsuhiro Shibata, Terence P Speed, Lincoln D Stein, Joshua M Stuart, Jon W Teague, Yasushi Totoki, Tatsuhiko Tsunoda, Alfonso Valencia, David A Wheeler, Honglong Wu, Shancen Zhao, Guangyu Zhou, Lincoln D Stein, Roderic Guigó, Tim J Hubbard, Yann Joly, Steven M Jones, Arek Kasprzyk, Mark Lathrop, Nuria López-Bigas, B F Francis Ouellette, Paul T Spellman, Jon W Teague, Gilles Thomas, Alfonso Valencia, Teruhiko Yoshida, Karen L Kennedy, Myles Axton, Stephanie O M Dyke, P Andrew Futreal, Daniela S Gerhard, Chris Gunter, Mark Guyer, Thomas J Hudson, John D McPherson, Linda J Miller, Brad Ozenberger, Kenna M Shaw, Arek Kasprzyk, Lincoln D Stein, Junjun Zhang, Syed A Haider, Jianxin Wang, Christina K Yung, Anthony Cros, Yong Liang, Saravanamuttu Gnaneshan, Jonathan Guberman, Jack Hsu, Martin Bobrow, Don R C Chalmers, Karl W Hasel, Yann Joly, Terry S H Kaan, Karen L Kennedy, Bartha M Knoppers, William W Lowrance, Tohru Masui, Pilar Nicolás, Emmanuelle Rial-Sebbag, Laura Lyman Rodriguez, Catherine Vergely, Teruhiko Yoshida, Sean M Grimmond, Andrew V Biankin, David D L Bowtell, Nicole Cloonan, Anna deFazio, James R Eshleman, Dariush Etemadmoghadam, Brooke B Gardiner, James G Kench, Aldo Scarpa, Robert L Sutherland, Margaret A Tempero, Nicola J Waddell, Peter J Wilson, John D McPherson, Steve Gallinger, Ming-Sound Tsao, Patricia A Shaw, Gloria M Petersen, Debabrata Mukhopadhyay, Lynda Chin, Ronald A DePinho, Sarah Thayer, Lakshmi Muthuswamy, Kamran Shazand, Timothy Beck, Michelle Sam, Lee Timms, Vanessa Ballin, Youyong Lu, Jiafu Ji, Xiuqing Zhang, Feng Chen, Xueda Hu, Guangyu Zhou, Qi Yang, Geng Tian, Lianhai Zhang, Xiaofang Xing, Xianghong Li, Zhenggang Zhu, Yingyan Yu, Jun Yu, Huanming Yang, Mark Lathrop, Jörg Tost, Paul Brennan, Ivana Holcatova, David Zaridze, Alvis Brazma, Lars Egevard, Egor Prokhortchouk, Rosamonde Elizabeth Banks, Mathias Uhlén, Anne Cambon-Thomsen, Juris Viksna, Fredrik Ponten, Konstantin Skryabin, Michael R Stratton, P Andrew Futreal, Ewan Birney, Ake Borg, Anne-Lise Børresen-Dale, Carlos Caldas, John A Foekens, Sancha Martin, Jorge S Reis-Filho, Andrea L Richardson, Christos Sotiriou, Hendrik G Stunnenberg, Giles Thoms, Marc van de Vijver, Laura van't Veer, Fabien Calvo, Daniel Birnbaum, Hélène Blanche, Pascal Boucher, Sandrine Boyault, Christian Chabannon, Ivo Gut, Jocelyne D Masson-Jacquemier, Mark Lathrop, Iris Pauporté, Xavier Pivot, Anne Vincent-Salomon, Eric Tabone, Charles Theillet, Gilles Thomas, Jörg Tost, Isabelle Treilleux, Fabien Calvo, Paulette Bioulac-Sage, Bruno Clément, Thomas Decaens, Françoise Degos, Dominique Franco, Ivo Gut, Marta Gut, Simon Heath, Mark Lathrop, Didier Samuel, Gilles Thomas, Jessica Zucman-Rossi, Peter Lichter, Roland Eils, Benedikt Brors, Jan O Korbel, Andrey Korshunov, Pablo Landgraf, Hans Lehrach, Stefan Pfister, Bernhard Radlwimmer, Guido Reifenberger, Michael D Taylor, Christof von Kalle, Partha P Majumder, Rajiv Sarin, T S Rao, M K Bhan, Aldo Scarpa, Paolo Pederzoli, Rita A Lawlor, Massimo Delledonne, Alberto Bardelli, Andrew V Biankin, Sean M Grimmond, Thomas Gress, David Klimstra, Giuseppe Zamboni, Tatsuhiro Shibata, Yusuke Nakamura, Hidewaki Nakagawa, Jun Kusada, Tatsuhiko Tsunoda, Satoru Miyano, Hiroyuki Aburatani, Kazuto Kato, Akihiro Fujimoto, Teruhiko Yoshida, Elias Campo, Carlos López-Otín, Xavier Estivill, Roderic Guigó, Silvia de Sanjosé, Miguel A Piris, Emili Montserrat, Marcos González-Díaz, Xose S Puente, Pedro Jares, Alfonso Valencia, Heinz Himmelbauer, Victor Quesada, Silvia Bea, Michael R Stratton, P Andrew Futreal, Peter J Campbell, Anne Vincent-Salomon, Andrea L Richardson, Jorge S Reis-Filho, Marc van de Vijver, Gilles Thomas, Jocelyne D Masson-Jacquemier, Samuel Aparicio, Ake Borg, Anne-Lise Børresen-Dale, Carlos Caldas, John A Foekens, Hendrik G Stunnenberg, Laura van't Veer, Douglas F Easton, Paul T Spellman, Sancha Martin, Anna D Barker, Lynda Chin, Francis S Collins, Carolyn C Compton, Martin L Ferguson, Daniela S Gerhard, Gad Getz, Chris Gunter, Alan Guttmacher, Mark Guyer, D Neil Hayes, Eric S Lander, Brad Ozenberger, Robert Penny, Jane Peterson, Chris Sander, Kenna M Shaw, Terence P Speed, Paul T Spellman, Joseph G Vockley, David A Wheeler, Richard K Wilson, Thomas J Hudson, Lynda Chin, Bartha M Knoppers, Eric S Lander, Peter Lichter, Lincoln D Stein, Michael R Stratton, Warwick Anderson, Anna D Barker, Cindy Bell, Martin Bobrow, Wylie Burke, Francis S Collins, Carolyn C Compton, Ronald A DePinho, Douglas F Easton, P Andrew Futreal, Daniela S Gerhard, Anthony R Green, Mark Guyer, Stanley R Hamilton, Tim J Hubbard, Olli P Kallioniemi, Karen L Kennedy, Timothy J Ley, Edison T Liu, Youyong Lu, Partha Majumder, Marco Marra, Brad Ozenberger, Jane Peterson, Alan J Schafer, Paul T Spellman, Hendrik G Stunnenberg, Brandon J Wainwright, Richard K Wilson, Huanming Yang

International network of cancer genome projects

International Cancer Genome Consortium et al. Nature. .

Erratum in

  • Nature. 2010 Jun 17;465(7300):966. Himmelbaue, Heinz [corrected to Himmelbauer, Heinz]; Gardiner, Brooke A [corrected to Gardiner, Brooke B]; Cross, Anthony [corrected to Cros, Anthony]

Abstract

The International Cancer Genome Consortium (ICGC) was launched to coordinate large-scale cancer genome studies in tumours from 50 different cancer types and/or subtypes that are of clinical and societal importance across the globe. Systematic studies of more than 25,000 cancer genomes at the genomic, epigenomic and transcriptomic levels will reveal the repertoire of oncogenic mutations, uncover traces of the mutagenic influences, define clinically relevant subtypes for prognosis and therapeutic management, and enable the development of new cancer therapies.

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