Chronic Inflammatory Demyelinating Polyradiculoneuropathy
- PMID: 20393791
- DOI: 10.1007/s10875-010-9399-0
Chronic Inflammatory Demyelinating Polyradiculoneuropathy
Abstract
Chronic inflammatory demyelinating polyradiculoneuropathy is a chronic progressive or relapsing and remitting disease with a prevalence of up to 8.9 per 100,000.
Methods: This review discusses possible mechanisms, none of which are proven, and describes the evidence for its treatment.
Results: Cochrane Reviews provide evidence that corticosteroids, intravenous immunoglobulin, and plasma exchange are effective short-term treatments. Attempts to confirm the efficacy of other immunosuppressant agents have not been successful, although they are often used in people whose disease is resistant to the first-line treatments.
Conclusions: More and better trials are needed.
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