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Review
. 2010 May:30 Suppl 1:S70-3.
doi: 10.1007/s10875-010-9399-0.

Chronic Inflammatory Demyelinating Polyradiculoneuropathy

Richard Hughes  1
Affiliations
Review

Chronic Inflammatory Demyelinating Polyradiculoneuropathy

Richard Hughes. J Clin Immunol. 2010 May.

Abstract

Chronic inflammatory demyelinating polyradiculoneuropathy is a chronic progressive or relapsing and remitting disease with a prevalence of up to 8.9 per 100,000.

Methods: This review discusses possible mechanisms, none of which are proven, and describes the evidence for its treatment.

Results: Cochrane Reviews provide evidence that corticosteroids, intravenous immunoglobulin, and plasma exchange are effective short-term treatments. Attempts to confirm the efficacy of other immunosuppressant agents have not been successful, although they are often used in people whose disease is resistant to the first-line treatments.

Conclusions: More and better trials are needed.

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