Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2010 Apr;58(4):650-7.
doi: 10.1111/j.1532-5415.2010.02769.x.

Missed opportunities for osteoporosis treatment in patients hospitalized for hip fracture

Affiliations

Missed opportunities for osteoporosis treatment in patients hospitalized for hip fracture

Lee A Jennings et al. J Am Geriatr Soc. 2010 Apr.

Abstract

Objectives: Although osteoporosis treatment can dramatically reduce fracture risk, rates of treatment after hip fracture remain low. In-hospital initiation of recommended medications has improved outcomes in heart disease; hospitalization for hip fracture may represent a similar opportunity for improvement. The objective of this study was to examine rates of in-hospital treatment with a combination of calcium and vitamin D (Cal+D) and antiresorptive or bone-forming medications in patients hospitalized for hip fractures

Design: Observational cohort.

Setting: Three hundred eighteen hospitals in the United States.

Participants: Fifty-one thousand three hundred forty-six patients aged 65 and older hospitalized for osteoporotic hip fracture.

Measurements: In-hospital administration of Cal+D and antiresorptive or bone-forming medications.

Results: Three thousand four hundred five patients (6.6%) received Cal+D anytime after a procedure to correct femoral fracture; 3,763 patients (7.3%) received antiresorptive or bone-forming medications. Only 1,023 patients (2.0%) were prescribed ideal therapy, receiving Cal+D and an antiresorptive or bone-forming medication. Treatment rates remained low across virtually all patient-, provider-, and hospital-level characteristics. The strongest predictor of treatment with Cal+D was the receipt of an antiresorptive or bone-forming medication (adjusted odds ratio=5.50, 95% confidence interval=4.84-6.25), but only 27.2% of patients who received these medications also received Cal+D.

Conclusion: Rates of in-hospital initiation of osteoporosis treatment for patients with hip fracture are low and may represent an opportunity to improve care.

Keywords: Calcium; Hip Fracture; Osteoporosis; Vitamin D.

PubMed Disclaimer

Conflict of interest statement

Conflict of Interest Disclosures:

Figures

Figure 1
Figure 1
Criteria Used to Define the Final Cohort of Patients Eligible for Osteoporosis Treatment.
Figure 2
Figure 2
Rates of Inpatient Treatment After Hip Fracture Surgery Prophylactic Antibiotics for Surgery and DVT prophylaxis rates were determined for the day of surgery and post-operative day 1.

Comment in

  • Preventing the next "bone event".
    Adler RA. Adler RA. J Am Geriatr Soc. 2010 Apr;58(4):762-4. doi: 10.1111/j.1532-5415.2010.02778.x. J Am Geriatr Soc. 2010. PMID: 20398160 No abstract available.

References

    1. Fast Facts on Osteoporosis. National Institute of Arthritis, Musculoskeletal and Skin Diseases. 2009. Apr 13, Available from http://www.nof.org/osteoporosis/diseasefacts.htm.
    1. Clinician's Guide to Prevention and Treatment of Osteoporosis. National Osteoporosis Foundation. 2009. Apr 13, Available from http://www.nof.org/professionals/NOF_Clinicians_Guide.pdf.
    1. Osteoporosis prevention, diagnosis, and therapy. JAMA. 2001 Feb 14;285(6):785–795. - PubMed
    1. Bliuc D, Nguyen ND, Milch VE, et al. Mortality risk associated with low-trauma osteoporotic fracture and subsequent fracture in men and women. JAMA. 2009 Feb 4;301(5):513–521. - PubMed
    1. Center JR, Bliuc D, Nguyen TV, et al. Risk of subsequent fracture after low-trauma fracture in men and women. JAMA. 2007 Jan 24;297(4):387–394. - PubMed

Publication types

MeSH terms