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. 2010 Jul;121(1-2):462-6.
doi: 10.1016/j.jsbmb.2010.03.091. Epub 2010 Apr 22.

Low vitamin D status is associated with physical inactivity, obesity and low vitamin D intake in a large US sample of healthy middle-aged men and women

K Brock  1 , W-Y Huang, D R Fraser, L Ke, M Tseng, R Stolzenberg-Solomon, U Peters, J Ahn, M Purdue, R S Mason, C McCarty, R G Ziegler, B Graubard
Affiliations

Low vitamin D status is associated with physical inactivity, obesity and low vitamin D intake in a large US sample of healthy middle-aged men and women

K Brock et al. J Steroid Biochem Mol Biol. 2010 Jul.

Abstract

The aim of this study was to investigate modifiable predictors of vitamin D status in healthy individuals, aged 55-74, and living across the USA. Vitamin D status [serum 25-hydroxyvitamin D (25(OH)D)] was measured along with age and season at blood collection, demographics, anthropometry, physical activity (PA), diet, and other lifestyle factors in 1357 male and 1264 female controls selected from the Prostate, Lung, Colorectal, and Ovarian Cancer Screening Trial (PLCO) cohort. Multivariate linear and logistic regression analyses were used to identify associations with vitamin D status. Three%, 29% and 79% of the population had serum 25(OH)D levels<25, <50 and <80 nmol/L, respectively. The major modifiable predictors of low vitamin D status were low vitamin D dietary and supplement intake, body mass index (BMI) >30 kg/m2, physical inactivity (PA) and low milk and calcium supplement intake. In men, 25(OH)D was determined more by milk intake on cereal and in women, by vitamin D and calcium supplement and menopausal hormone therapy (MHT) use. Thus targeting an increase in vigorous activity and vitamin D and calcium intake and decreasing obesity could be public health interventions independent of sun exposure to improve vitamin D status in middle-aged Americans.

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Figures

Figure 1
Figure 1
Seasonal variation of serum 25(OH)D concentrations in US men and women: including with and without use of menopausal hormone therapy (MHT) in women
Figure 2
Figure 2
Seasonal variation of serum 25(OH)D concentrations in US men and women showing intaake or not of vitamin D supplement use
See this image and copyright information in PMC

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