Overview and historical perspective of four papers presented on research related to the endogenous opioid system

Affiliations

Comment

Mary Jeanne Kreek. Drug Alcohol Depend. 2010.

. 2010 May 1;108(3):195-9.

doi: 10.1016/j.drugalcdep.2010.03.003. Epub 2010 Apr 18.

¹ The Laboratory of the Biology of Addictive Diseases, The Rockefeller University, New York, NY 10065, USA. kreek@rockefeller.edu

No abstract available

Comment on

The endogenous opioid system: a common substrate in drug addiction.
Trigo JM, Martin-García E, Berrendero F, Robledo P, Maldonado R. Trigo JM, et al. Drug Alcohol Depend. 2010 May 1;108(3):183-94. doi: 10.1016/j.drugalcdep.2009.10.011. Epub 2009 Nov 28. Drug Alcohol Depend. 2010. PMID: 19945803 Review.
OPRM1 SNP (A118G): involvement in disease development, treatment response, and animal models.
Mague SD, Blendy JA. Mague SD, et al. Drug Alcohol Depend. 2010 May 1;108(3):172-82. doi: 10.1016/j.drugalcdep.2009.12.016. Epub 2010 Jan 13. Drug Alcohol Depend. 2010. PMID: 20074870 Free PMC article. Review.
Opioid pharmaceuticals and addiction: the issues, and research directions seeking solutions.
Walwyn WM, Miotto KA, Evans CJ. Walwyn WM, et al. Drug Alcohol Depend. 2010 May 1;108(3):156-65. doi: 10.1016/j.drugalcdep.2010.01.001. Epub 2010 Feb 25. Drug Alcohol Depend. 2010. PMID: 20188495 Free PMC article. Review.
Regulation of opioid receptors by endocytic membrane traffic: mechanisms and translational implications.
von Zastrow M. von Zastrow M. Drug Alcohol Depend. 2010 May 1;108(3):166-71. doi: 10.1016/j.drugalcdep.2010.02.014. Epub 2010 Mar 24. Drug Alcohol Depend. 2010. PMID: 20338697 Free PMC article. Review.

1. Bart G, Heilig M, LaForge KS, Pollak L, Leal SM, Ott J, Kreek MJ. Substantial attributable risk related to a functional mu-opioid receptor gene polymorphism in association with heroin addiction in central Sweden. Mol Psychiatry. 2004;9:547–549. - PMC - PubMed
1. Bart G, Kreek MJ, Ott J, LaForge KS, Proudnikov D, Pollak L, Heilig M. Increased attributable risk related to a functional mu-opioid receptor gene polymorphism in association with alcohol dependence in central Sweden. Neuropsychopharmacology. 2005;30:417–422. - PubMed
1. Bergen AW, Kokoszka J, Peterson R, Long JC, Virkkunen M, Linnoila M, Goldman D. Mu opioid receptor gene variants: lack of association with alcohol dependence. Mol Psychiatry. 1997;2:490–494. - PubMed
1. Berrettini WH, Hoehe MR, Ferrada TN, Gottheil E. Human mu opioid receptor gene polymorphisms and vulnerability to substance abuse. Addict Biol. 1997;2:303–308. - PubMed
1. Bond C, LaForge KS, Tian M, Melia D, Zhang S, Borg L, Gong J, Schluger J, Strong JA, Leal SM, Tischfield JA, Kreek MJ, Yu L. Single nucleotide polymorphism in the human mu opioid receptor gene alters beta-endorphin binding and activity: Possible implications for opiate addiction. Proc Natl Acad Sci USA. 1998;95:9608–9613. - PMC - PubMed