Long-lasting maternal depression and child growth at 4 years of age: a cohort study
- PMID: 20400093
- PMCID: PMC2937222
- DOI: 10.1016/j.jpeds.2010.03.008
Long-lasting maternal depression and child growth at 4 years of age: a cohort study
Abstract
Objective: To investigate the association between sustained maternal depression at 12, 24, and 48 months post-partum and child anthropometry at age of 4 years.
Study design: A total of 99.2% of the 4287 children born in 2004 in Pelotas, Brazil, were enrolled in a cohort study. At 3, 12, 24, and 48 months, mothers were interviewed and provided information on several characteristics. Maternal depression was investigated through the Edinburgh Postnatal Depression Scale (EPDS). Weight-for-age, height-for-age, and weight-for-height z-scores at 48 months, according to World Health Organization growth curves, were the outcomes. Multivariate analyses were conducted through logistic regression.
Results: At the 48-month follow-up, of the 3792 children, prevalence of underweight was 1.7%; stunting, 3.6%; wasting, 0.6%; and overweight, 12.2%. Depression (EPDS>or=13) was observed in 17.9% of the 3748 mothers. Of the mothers, 4.7% were persistently depressed at the 12-, 24-, and 48-month visits. In crude analyses, maternal depression was positively associated with underweight and stunting. After adjustment, maternal depression was not associated with any of the anthropometric indices.
Conclusion: Long-lasting maternal depression at 12, 24, and 48 months post-partum is not a risk factor for impaired child growth or overweight at age of 4 years.
Copyright (c) 2010 Mosby, Inc. All rights reserved.
Comment in
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Maternal depression and child growth: definitional issues, longitudinal trajectories, and analytic considerations.J Pediatr. 2010 Sep;157(3):359-60. doi: 10.1016/j.jpeds.2010.04.061. Epub 2010 Jun 12. J Pediatr. 2010. PMID: 20542289 No abstract available.
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Are we adequately protecting vulnerable patients in longitudinal observational studies?J Pediatr. 2011 Jun;158(6):1036-7; author reply 1037. doi: 10.1016/j.jpeds.2010.12.033. Epub 2011 Feb 6. J Pediatr. 2011. PMID: 21300370 No abstract available.
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