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Comment
. 2010 Apr 27;107(17):7627-8.
doi: 10.1073/pnas.1003433107. Epub 2010 Apr 16.

Addressing microbial organelles: a short peptide directs enzymes to the interior

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Comment

Addressing microbial organelles: a short peptide directs enzymes to the interior

Sabine Heinhorst et al. Proc Natl Acad Sci U S A. .
No abstract available

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Conflict of interest statement

The authors declare no conflict of interest.

Figures

Fig. 1.
Fig. 1.
Targeting of sequestered proteins to the interior of BMCs. As described in PNAS (5), a short extension of ≈20 amino acids found on the N terminus of PduP directs the enzyme to the lumen of the Pdu BMC. (A and B) Fan et al. (5) propose that the N-terminal segment binds specific sites on the interior surface of shell protein assemblies. (C) Additional protein interactions are likely to occur between shell-anchored proteins and those found deeper in the BMC interior and would account for the solid appearance of BMC interiors observed with various imaging methods.

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References

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