Comment
doi: 10.1016/j.cell.2010.03.047.
Ubiquitin gets CARDed
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- PMID: 20403317
- DOI: 10.1016/j.cell.2010.03.047
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Comment
Ubiquitin gets CARDed
Cell.
.
Free article
Abstract
Ubiquitin-dependent processes are critical for propagating antiviral defense signals during viral infection. In this issue, Zeng et al. (2010) describe how viral RNA and unanchored ubiquitin chains conspire to promote activation of RIG-I and the host cell's antiviral transcriptional program.
Copyright 2010 Elsevier Inc. All rights reserved.
Comment on
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Reconstitution of the RIG-I pathway reveals a signaling role of unanchored polyubiquitin chains in innate immunity.Cell. 2010 Apr 16;141(2):315-30. doi: 10.1016/j.cell.2010.03.029. Cell. 2010. PMID: 20403326 Free PMC article.
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