The hidden rhythms of the dividing cell
- PMID: 20403319
- DOI: 10.1016/j.cell.2010.03.042
The hidden rhythms of the dividing cell
Abstract
The cell divides in a series of discrete steps that occur in a specific order. Lu and Cross (2010) now propose that cell-cycle events are ordered by a regulatory system in which a master oscillator, based on cyclin-dependent kinases, entrains a series of peripheral oscillators controlling individual events.
Copyright 2010 Elsevier Inc. All rights reserved.
Comment on
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Periodic cyclin-Cdk activity entrains an autonomous Cdc14 release oscillator.Cell. 2010 Apr 16;141(2):268-79. doi: 10.1016/j.cell.2010.03.021. Cell. 2010. PMID: 20403323 Free PMC article.
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