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. 1991 Jun;118(6):879-84.
doi: 10.1016/s0022-3476(05)82198-5.

Continuous venovenous hemofiltration in the management of acute decompensation in inborn errors of metabolism

G N Thompson  1 , W W Butt, F A Shann, D M Kirby, R D Henning, D W Howells, A Osborne
Affiliations

Continuous venovenous hemofiltration in the management of acute decompensation in inborn errors of metabolism

G N Thompson et al. J Pediatr. 1991 Jun.

Abstract

Continuous venovenous hemofiltration was used to treat two neonates, one with maple syrup urine disease and the other with an inborn error of long-chain fatty acid oxidation. The latter infant had hypoglycemia, hyperammonemia and lactic acidosis. In both cases, acceptable biochemical control was achieved within 8 hours. This therapy offers the potential to overcome acute crises rapidly in a wide range of inborn errors of intermediary metabolism.

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