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Case Reports
. 2010 May;16(5):837-9.
doi: 10.3201/eid1605.091815.

Nosocomial outbreak of Crimean-Congo hemorrhagic fever, Sudan

Imadeldin E Aradaib  1 , Bobbie R Erickson, Mubarak E Mustafa, Marina L Khristova, Nageeb S Saeed, Rehab M Elageb, Stuart T Nichol
Affiliations
Case Reports

Nosocomial outbreak of Crimean-Congo hemorrhagic fever, Sudan

Imadeldin E Aradaib et al. Emerg Infect Dis. 2010 May.

Abstract

To confirm the presence of Crimean-Congo hemorrhagic fever in Sudan, we tested serum of 8 patients with hemorrhagic fever in a rural hospital in 2008. Reverse transcription-PCR identified Crimean-Congo hemorrhagic fever virus. Its identification as group III lineage indicated links to virus strains from South Africa, Mauritania, and Nigeria.

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Figures

Figure
Figure
Phylogenetic relationship of Crimean-Congo hemorrhagic fever virus (CCHFV) full-length small (S) segments. Phylogenetic analysis used 47 full-length CCHFV S segments available in GenBank. GARLI (v0.96b8) (9) with default settings was used to generate a maximum-likelihood tree with bootstrap support values from 1,000 replicates. From the analysis, a 50% majority-rule tree was constructed. Virus strains from Sudan patients 1, 2, 3, 6, 7, 8, and 9 (GenBank accession no. GQ862371) were identical, and the virus sequence from patient 4 (GenBank accession no. GQ862372) differed by 1 nt. Each strain is listed by its location, strain name, and year of isolation, when available. Boldface indicates strains from Sudan; braces indicate previously described genetic lineages (8).
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References

    1. Hoogstraal H. The epidemiology of tick-borne Crimean-Congo haemorrhagic fever in Asia, Europe and Africa. J Med Entomol. 1979;15:307–417. - PubMed
    1. Swanepoel R. Crimean-Congo haemorrhagic fever. In: Coetzer JA, Thomson GR, Tustin RC, editors. Infectious diseases of livestock with special reference to southern Africa. Cape Town (South Africa): Oxford University Press; 1994. p. 723–9.
    1. Whitehouse CA. Crimean-Congo hemorrhagic fever. Antiviral Res. 2004;64:145–60. 10.1016/j.antiviral.2004.08.001 - DOI - PubMed
    1. Ergonul O. Crimean-Congo haemorrhagic fever. Lancet Infect Dis. 2006;6:203–14. 10.1016/S1473-3099(06)70435-2 - DOI - PMC - PubMed
    1. Schmaljohn CS, Nichol ST. Bunyaviridae. In: Knipe DM, Howley PM, Griffin DE, Lamb RA, Martin MA, Roizman B, et al., editors. Fields virology, 5th ed. Philadelphia: Lippincott, Williams, and Wilkins; 2007. p. 1741–89.

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