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. 2010 Apr 21;2(28):28ps19.
doi: 10.1126/scitranslmed.3001056.

Drug resistance, epigenetics, and tumor cell heterogeneity

Timothy Hoey  1
Affiliations

Drug resistance, epigenetics, and tumor cell heterogeneity

Timothy Hoey. Sci Transl Med. .

Abstract

The resistance of cancer cells to various therapeutic agents and modalities is a crucial issue in clinical oncology. A recent Cell paper highlights how changes at the chromatin level control drug sensitivity and provides insight into more effective strategies for treating cancer with combination therapies.

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