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Case Reports
. 2010 Jan;14(1):54-6.

Symptomatic splenoma (hamartoma) of the spleen. A case report

I Tsitouridis  1 , M Michaelides, K Tsitouridis, I Davidis, I Efstratiou
Affiliations
Case Reports

Symptomatic splenoma (hamartoma) of the spleen. A case report

I Tsitouridis et al. Hippokratia. 2010 Jan.

Abstract

Hamartomas of the spleen (splenomas) are very rare benign tumors composed of an aberrant mixture of normal splenic elements. Herein we present a unique case of a symptomatic non-palpable splenoma in a 64-year-old female patient presented with anemia and thrombocytopenia and we describe imaging findings in ultrasound, computed tomography and magnetic resonance imaging. To our knowledge, this is the first case of a relatively small splenic hamartoma (35 mm at histopathology) associated with thrombocytopenia and anemia that resolved completely several months after splenectomy.

Keywords: hamartoma; spleen; splenoma.

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Figures

Figure 1
Figure 1. US of the splenic lesion, demonstrating a well defined hyperechoic lesion in the upper pole of the spleen (A) with increased internal vascularization in Power Doppler (B).
Figure 2
Figure 2. Triphasic spiral CT demonstrating the lesion with intense, inhomogeneous enhancement during arterial phase (A). In portal phase the lesion is hyperdense compared to normal splenic parenchyma (B). Delayed "wash out" is demonstrated in the delayed phase (C).
Figure 3
Figure 3. MRI of the lesion, with increased signal intensity relatively to the normal splenic parenchyma on axial T2-Haste images (A) and heterogeneous enhancement on axial T1-Flash images after intravenous administration of gadolinium (B).
Figure 4
Figure 4. A. Surgical specimen showing a well circumscribed lesion with a maximum diameter of 35mm in the spleen. B. Histological section showing the cells of red pulp of the lesion (HE X 200). C. Immunohistochemical staining showing the cells to react with factor CD-31.
See this image and copyright information in PMC

References

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