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. 2010 Apr 15;6(2):146-51.

Evaluation of the apnea-hypopnea index determined by the S8 auto-CPAP, a continuous positive airway pressure device, in patients with obstructive sleep apnea-hypopnea syndrome

Kanako Ueno  1 , Takatoshi Kasai, Gregory Brewer, Hisashi Takaya, Ken-ichi Maeno, Satoshi Kasagi, Fusae Kawana, Sugao Ishiwata, Koji Narui
Affiliations

Evaluation of the apnea-hypopnea index determined by the S8 auto-CPAP, a continuous positive airway pressure device, in patients with obstructive sleep apnea-hypopnea syndrome

Kanako Ueno et al. J Clin Sleep Med. .

Abstract

Objective: Continuous positive airway pressure (CPAP) has been established as an effective treatment for obstructive sleep apnea-hypopnea syndrome (OSAHS). Recently, several auto-CPAP devices that can detect upper airway obstructive events and provide information about residual events while patients are on CPAP have come into clinical use. The purpose of this study was to compare the apnea-hypopnea index (AHI) determined by the S8 auto-CPAP device with the AHI derived by polysomnography in patients with OSAHS.

Method: Consecutive patients with OSAHS titrated on S8 auto-CPAP were included. The correlation between AHI determined by manual scoring (AHI-PSG) and by S8 (AHIS8) during an overnight in-hospital polysomnogram with the patient on CPAP was assessed. Furthermore, the apnea index (Al) and the hypopnea index (HI) were evaluated separately.

Results: Seventy patients with OSAHS (94% men) were enrolled. The mean AHI on the diagnostic study was 51.9 +/- 2.4. During the titration, this device markedly suppressed the respiratory events (AHI-PSG, 4.2 +/- 0.4; AI, 1.9 +/- 0.3; HI, 2.3 +/- 0.3). On the other hand, the AHI-S8 was 9.9 +/- 0.6 (AI-S8, 2.4 +/- 0.3; HI-S8, 7.5 +/- 0.4). There was a strong correlation between the overall AHI-PSG and the AHI-S8 (r = 0.85, p < 0.001), with a stronger correlation in the apnea component AI-PSG and the AI-S8 (r = 0.93, p < 0.001), whereas there was a weaker correlation between the HI-PSG and the HI-S8 (r = 0.67, p <0.001).

Conclusions: Using the same airflow signals as those of the CPAP device, a strong correlation between the AHI-PSG and the AHI-S8 was observed. However, the correlation was weakened when the analysis was limited to the HI.

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Figures

Figure 1A
Figure 1A
Scatter plots of the apnea-hypopnea index (AHI) derived from the polysomnogram (AHI-PSG) and the AHI from the S8 auto-continuous positive airway pressure (CPAP) device (AHI-S8).
Figure 1B
Figure 1B
Bland-Altman plots according to the AHI.
Figure 2A
Figure 2A
Scatter plots of the apnea index (AI) derived from the polysomnogram (AI-PSG) and the AI from the S8 auto-continuous positive airway pressure device (AI-S8).
Figure 2B
Figure 2B
Bland-Altman plots according to the AI.
Figure 3A
Figure 3A
Scatter plots of the hypopnea index (HI) derived from the polysomnogram (HI-PSG) and the HI from the S8 auto-continuous positive airway pressure (CPAP) device (HI-S8).
Figure 3B
Figure 3B
Bland-Altman plots according to the HI. The Y axis indicates the difference between the HI-PSG and the HI-S8 ([HI-PSG]-[HI-S8]).
See this image and copyright information in PMC

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