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Comment
. 2010 Apr 20;18(4):506-7.
doi: 10.1016/j.devcel.2010.04.005.

Realizing the promise of RNAi high throughput screening

Chris Bakal  1 , Norbert Perrimon
Affiliations
Comment

Realizing the promise of RNAi high throughput screening

Chris Bakal et al. Dev Cell. .

Abstract

Recently reporting in Nature, Collinet et al. describes the application of quantitative multiparametric methods to a genome-wide RNAi screen for regulators of endocytosis. The study illustrates the power of this approach beyond the identification of new endocytic components to providing insights into the design principles of the endocytic system.

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Comment on

  • Systems survey of endocytosis by multiparametric image analysis.
    Collinet C, Stöter M, Bradshaw CR, Samusik N, Rink JC, Kenski D, Habermann B, Buchholz F, Henschel R, Mueller MS, Nagel WE, Fava E, Kalaidzidis Y, Zerial M. Collinet C, et al. Nature. 2010 Mar 11;464(7286):243-9. doi: 10.1038/nature08779. Epub 2010 Feb 28. Nature. 2010. PMID: 20190736

References

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    1. Collinet C, Stöter M, Bradshaw CR, Samusik N, Rink JC, Kenski D, Habermann B, Buchholz F, Henschel R, Mueller MS, et al. Nature. 2010;464:243–249. - PubMed
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