Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Review
. 2010 May;10(5):319-31.
doi: 10.1038/nrc2818.

Targeting brain cancer: advances in the molecular pathology of malignant glioma and medulloblastoma

Jason T Huse  1 , Eric C Holland
Affiliations
Review

Targeting brain cancer: advances in the molecular pathology of malignant glioma and medulloblastoma

Jason T Huse et al. Nat Rev Cancer. 2010 May.

Abstract

Malignant brain tumours continue to be the cause of a disproportionate level of morbidity and mortality across a wide range of individuals. The most common variants in the adult and paediatric populations - malignant glioma and medulloblastoma, respectively - have been the subject of increasingly intensive research over the past two decades that has led to considerable advances in the understanding of their basic biology and pathogenesis. This Review summarizes these developments in the context of the evolving notion of molecular pathology and discusses the implications that this work has on the design of new treatment regimens.

PubMed Disclaimer

References

    1. Cancer Res. 2006 Mar 1;66(5):2666-72 - PubMed
    1. Nature. 2006 Dec 7;444(7120):756-60 - PubMed
    1. Science. 1990 Nov 30;250(4985):1233-8 - PubMed
    1. Science. 2009 Oct 23;326(5952):572-4 - PubMed
    1. Proc Natl Acad Sci U S A. 1990 Nov;87(21):8602-6 - PubMed

LinkOut - more resources