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. 1991 May 16;351(6323):206-11.
doi: 10.1038/351206a0.

Two different microtubule-based motor activities with opposite polarities in kinetochores

A A Hyman  1 , T J Mitchison
Affiliations

Two different microtubule-based motor activities with opposite polarities in kinetochores

A A Hyman et al. Nature. .

Abstract

The movement of microtubules on the kinetochores of isolated chromosomes has been examined by video microscopy. Two different microtubule-based motors on the kinetochore were identified, which have opposite directions of movement. The activities of these two motors can be regulated by factors that can influence phosphorylation.

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