Antifungal susceptibility profile of human-pathogenic species of Lichtheimia
- PMID: 20421405
- PMCID: PMC2897292
- DOI: 10.1128/AAC.01270-09
Antifungal susceptibility profile of human-pathogenic species of Lichtheimia
Abstract
Forty-four isolates belonging to human pathogenic species of Lichtheimia were tested against nine antifungal agents by using the EUCAST methodology. No remarkable differences were found between the clinical species, although L. ramosa showed slightly higher MICs for all drugs. Amphotericin B was the most active drug. Among azole drugs, posaconazole had the best activity in vitro and voriconazole was inactive. Echinocandins showed activity for some isolates, suggesting a potential role in combination therapy.
Similar articles
-
In vitro activity of antifungals against Zygomycetes.Clin Microbiol Infect. 2009 Oct;15 Suppl 5:71-6. doi: 10.1111/j.1469-0691.2009.02984.x. Clin Microbiol Infect. 2009. PMID: 19754762 Review.
-
In Vitro Activity of Isavuconazole and Comparators against Clinical Isolates of the Mucorales Order.Antimicrob Agents Chemother. 2015 Dec;59(12):7735-42. doi: 10.1128/AAC.01919-15. Epub 2015 Oct 5. Antimicrob Agents Chemother. 2015. PMID: 26438494 Free PMC article.
-
Comparison of the EUCAST and CLSI Broth Microdilution Methods for Testing Isavuconazole, Posaconazole, and Amphotericin B against Molecularly Identified Mucorales Species.Antimicrob Agents Chemother. 2015 Dec;59(12):7882-7. doi: 10.1128/AAC.02107-15. Epub 2015 Oct 5. Antimicrob Agents Chemother. 2015. PMID: 26438489 Free PMC article.
-
Activity of posaconazole and other antifungal agents against Mucorales strains identified by sequencing of internal transcribed spacers.Antimicrob Agents Chemother. 2009 Apr;53(4):1686-9. doi: 10.1128/AAC.01467-08. Epub 2009 Jan 26. Antimicrob Agents Chemother. 2009. PMID: 19171801 Free PMC article.
-
In vitro antifungal activities of voriconazole and reference agents as determined by NCCLS methods: review of the literature.Mycopathologia. 2001;150(3):101-15. doi: 10.1023/a:1010954803886. Mycopathologia. 2001. PMID: 11469757 Review.
Cited by
-
Direct Visualization of Fungal Burden in Filamentous Fungus-Infected Silkworms.J Fungi (Basel). 2021 Feb 13;7(2):136. doi: 10.3390/jof7020136. J Fungi (Basel). 2021. PMID: 33668495 Free PMC article.
-
Antifungal susceptibility and phylogeny of opportunistic members of the order mucorales.J Clin Microbiol. 2012 Jan;50(1):66-75. doi: 10.1128/JCM.06133-11. Epub 2011 Nov 9. J Clin Microbiol. 2012. PMID: 22075600 Free PMC article.
-
Lichtheimia ramosa: A Fatal Case of Mucormycosis.Can Respir J. 2016;2016:2178218. doi: 10.1155/2016/2178218. Epub 2016 Mar 29. Can Respir J. 2016. PMID: 27445521 Free PMC article.
-
A rare intestinal mucormycosis caused by Lichtheimia ramosa in a patient with diabetes: a case report.Front Med (Lausanne). 2024 Oct 16;11:1435239. doi: 10.3389/fmed.2024.1435239. eCollection 2024. Front Med (Lausanne). 2024. PMID: 39478820 Free PMC article.
-
Expression Patterns in Reductive Iron Assimilation and Functional Consequences during Phagocytosis of Lichtheimia corymbifera, an Emerging Cause of Mucormycosis.J Fungi (Basel). 2021 Apr 3;7(4):272. doi: 10.3390/jof7040272. J Fungi (Basel). 2021. PMID: 33916756 Free PMC article.
References
-
- Aberkane, A., M. Cuenca-Estrella, A. Gomez-Lopez, E. Petrikkou, E. Mellado, A. Monzon, and J. L. Rodriguez-Tudela. 2002. Comparative evaluation of two different methods of inoculum preparation for antifungal susceptibility testing of filamentous fungi. J. Antimicrob. Chemother. 50:719-722. - PubMed
-
- Alastruey-Izquierdo, A., M. V. Castelli, I. Cuesta, A. Monzon, M. Cuenca-Estrella, and J. L. Rodriguez-Tudela. 2009. Activity of posaconazole and other antifungal agents against Mucorales strains identified by sequencing of internal transcribed spacers. Antimicrob. Agents Chemother. 53:1686-1689. - PMC - PubMed
Publication types
MeSH terms
Substances
LinkOut - more resources
Full Text Sources
Molecular Biology Databases