[Nausea and vomiting during treatment with cytostatics]

Abstract

Combination chemotherapy can often induce severe side effects such as nausea and vomiting. These unpleasant symptoms can delay or stop potentially curative therapy. Metoklopramid has traditionally been the most potent antiemetic drug, either given in doses of 20-50 mg or as high doses combined with dexamethazone and diazepam. The authors review antiemetic regimens and make a recommendation on antiemetic treatment.