Role of C-reactive protein in contributing to increased cardiovascular risk in metabolic syndrome

doi:10.1007/s11883-010-0098-3

Review

. 2010 Mar;12(2):110-8.

doi: 10.1007/s11883-010-0098-3.

Role of C-reactive protein in contributing to increased cardiovascular risk in metabolic syndrome

Sridevi Devaraj¹, Simona Valleggi, David Siegel, Ishwarlal Jialal

Affiliations

PMID: 20425246
PMCID: PMC2854398
DOI: 10.1007/s11883-010-0098-3

Review

Role of C-reactive protein in contributing to increased cardiovascular risk in metabolic syndrome

Sridevi Devaraj et al. Curr Atheroscler Rep. 2010 Mar.

. 2010 Mar;12(2):110-8.

doi: 10.1007/s11883-010-0098-3.

Authors

Sridevi Devaraj¹, Simona Valleggi, David Siegel, Ishwarlal Jialal

Affiliation

¹ University of California Davis Medical Center, Sacramento, CA 95817, USA.

PMID: 20425246
PMCID: PMC2854398
DOI: 10.1007/s11883-010-0098-3

Erratum in

Correction to: Role of C-Reactive Protein in Contributing to Increased Cardiovascular Risk in Metabolic Syndrome.
Devaraj S, Valleggi S, Siegel D, Jialal I. Devaraj S, et al. Curr Atheroscler Rep. 2019 Jan 25;21(1):4. doi: 10.1007/s11883-019-0769-7. Curr Atheroscler Rep. 2019. PMID: 30680541 Free PMC article.

Abstract

Metabolic syndrome is associated with increased propensity for diabetes and cardiovascular disease. Low-grade inflammation is characteristic of metabolic syndrome. C-reactive protein, the best characterized biomarker of inflammation, is also an independent predictor of future cardiovascular events. This review outlines the role of high-sensitivity C-reactive protein in contributing to increased cardiovascular risk in metabolic syndrome by inducing endothelial cell dysfunction and activating monocytes.

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References

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[1] Reaven GM. The insulin resistance syndrome: definition and dietary approaches to treatment. Annu Rev Nutr. 2005;25:391–406. doi: 10.1146/annurev.nutr.24.012003.132155. - DOI - PubMed

[2] Reaven GM. The insulin resistance syndrome: definition and dietary approaches to treatment. Annu Rev Nutr. 2005;25:391–406. doi: 10.1146/annurev.nutr.24.012003.132155. - DOI - PubMed

[3] Eckel RH, Grundy SM, Zimmet PZ. The metabolic syndrome. Lancet. 2005;365:1415–1428. doi: 10.1016/S0140-6736(05)66378-7. - DOI - PubMed

[4] Eckel RH, Grundy SM, Zimmet PZ. The metabolic syndrome. Lancet. 2005;365:1415–1428. doi: 10.1016/S0140-6736(05)66378-7. - DOI - PubMed

[5] Haffner S, Cassells HB. Metabolic syndrome—a new risk factor of coronary heart disease? Diabetes Obes Metab. 2003;5:359–370. doi: 10.1046/j.1463-1326.2003.00290.x. - DOI - PubMed

[6] Haffner S, Cassells HB. Metabolic syndrome—a new risk factor of coronary heart disease? Diabetes Obes Metab. 2003;5:359–370. doi: 10.1046/j.1463-1326.2003.00290.x. - DOI - PubMed

[7] Expert Panel on Detection, Evaluation, and Treatment of High Blood Cholesterol in Adults Executive Summary of the Third Report of the National Cholesterol Education Program (NCEP) Expert Panel on Detection, Evaluation, and Treatment of High Blood Cholesterol in Adults (Adult Treatment Panel III. JAMA. 2001;285:2486–2497. doi: 10.1001/jama.285.19.2486. - DOI - PubMed

[8] Expert Panel on Detection, Evaluation, and Treatment of High Blood Cholesterol in Adults Executive Summary of the Third Report of the National Cholesterol Education Program (NCEP) Expert Panel on Detection, Evaluation, and Treatment of High Blood Cholesterol in Adults (Adult Treatment Panel III. JAMA. 2001;285:2486–2497. doi: 10.1001/jama.285.19.2486. - DOI - PubMed

[9] Ford ES. Prevalence of the metabolic syndrome defined by the International Diabetes Federation among adults in the U.S. Diabetes Care. 2005;28:2745–2749. doi: 10.2337/diacare.28.11.2745. - DOI - PubMed

[10] Ford ES. Prevalence of the metabolic syndrome defined by the International Diabetes Federation among adults in the U.S. Diabetes Care. 2005;28:2745–2749. doi: 10.2337/diacare.28.11.2745. - DOI - PubMed

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Role of C-reactive protein in contributing to increased cardiovascular risk in metabolic syndrome

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Role of C-reactive protein in contributing to increased cardiovascular risk in metabolic syndrome

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