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. 2010 Winter;12(1):52-5.

Transitional cell carcinoma within a calyceal diverticulum associated with stone disease

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Transitional cell carcinoma within a calyceal diverticulum associated with stone disease

Jack M Zuckerman et al. Rev Urol. 2010 Winter.

Abstract

We report a case of transitional cell carcinoma (TCC) discovered within a calyceal diverticulum at the time of percutaneous nephrolithotomy. The stones and tumor were endoscopically removed and the diverticular cavity fulgurated. Pathologic analysis demonstrated low-grade TCC. A subsequent laparoscopic radical nephroureterectomy was performed and high-grade TCC invading the parenchyma was found. This case demonstrates the potential for TCC to develop in stone-containing calyceal diverticula and also the potential for coexistence of different grades of TCC within the involved renal unit.

Keywords: Calyceal diverticulum; Percutaneous nephrolithotomy; Stone; Transitional cell carcinoma; Urinary tract infection; Urolithiasis.

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Figures

Figure 1
Figure 1
Computed tomography of the abdomen supine (top) and prone (bottom) demonstrating a 3 cm × 3 cm calyceal diverticulum containing stones.
Figure 2
Figure 2
Retrograde pyelogram.
Figure 3
Figure 3
Endoscopy image captured during percutaneous nephrolithotomy of papillary lesions within the calyceal diverticulum.

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