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. 2010 Apr;18(4):197-201.
doi: 10.1007/BF03091761.

The effect of insulin on the heart : Part 1: Effects on metabolism and function

L J Klein  1 , F C Visser
Affiliations

The effect of insulin on the heart : Part 1: Effects on metabolism and function

L J Klein et al. Neth Heart J. 2010 Apr.

Abstract

Positive inotropic effects of insulin were described early after the isolation of insulin from the pancreas but data on the effect of insulin on the heart are conflicting. Systemic insulin administration results in a reduction in circulating free fatty acids and an improvement in myocardial glucose uptake, which causes an efficiency improvement in the myocardial cell. There is strong evidence that insulin administration results in functional improvement in dysfunctional myocardium. (Neth Heart J 2010;18:197-201.).

Keywords: Heart; Heart Failure; Insulin; Metabolism; Ventribular Function.

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