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. 1991 Mar;71(1):47-50.

[Therapeutic trial with ivermectin in loiasis with medium and high microfilaremia]

[Article in French]
B Carme  1 , B Ebikili, A Mbitsi, N Copin
Affiliations
  • PMID: 2043000

[Therapeutic trial with ivermectin in loiasis with medium and high microfilaremia]

[Article in French]
B Carme et al. Ann Soc Belg Med Trop. 1991 Mar.

Abstract

Treatment with ivermectin at the dosage of 200 microgram/kg in 28 Congolese loiasis patients led to an important decrease of the microfilaremia on day 7, with a reduction of about 90% of the initial parasite load. However, no negativation was observed and, moreover, the parasitemia did not change from day 7 to day 14. Tolerance was quite good, but weak to moderate reactions, linked to the lysis of the microfilariae, were observed in one third of the patients with a microfilaremia greater or equal to 2,500/mm3.

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