Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Review
. 2010 May;26(5):705-13.
doi: 10.1016/j.arthro.2009.12.011.

Bioabsorbable versus metallic interference screw fixation in anterior cruciate ligament reconstruction: a meta-analysis of randomized controlled trials

Chao Shen  1 , Sheng-Dan Jiang, Lei-Sheng Jiang, Li-Yang Dai
Affiliations
Review

Bioabsorbable versus metallic interference screw fixation in anterior cruciate ligament reconstruction: a meta-analysis of randomized controlled trials

Chao Shen et al. Arthroscopy. 2010 May.

Abstract

Purpose: The aim of the study was to investigate the outcomes between bioabsorbable and metallic screw fixation in anterior cruciate ligament (ACL) reconstruction.

Methods: Randomized controlled trials (RCTs) comparing bioabsorbable versus metallic screw fixation in single-bundle ACL reconstruction were identified systematically, and the outcomes were analyzed in terms of infection rate, knee joint effusion, Lysholm score, International Knee Documentation Committee final score, pivot-shift test, and KT-1000/-2000 arthrometer (MEDmetric, San Diego, CA) measurements. The type of grafts was ignored in the meta-analysis. Standard mean difference (SMD) or risk ratio (RR) with 95% confidence interval (CI) was calculated by a fixed-effects or random-effects model. Heterogeneity across the studies was also assessed.

Results: We included 10 studies comprising 790 patients who were treated by bioabsorbable versus metallic screw fixation for single-bundle ACL reconstruction. The meta-analyzed results of these studies showed that there was no statistically significant difference between bioabsorbable and metallic screw fixation in infection rate (RR, 0.91; P = .87; 320 patients in 5 studies), KT-1000/2000 arthrometer testing (SMD, -0.01; P = .95; 438 patients in 7 studies), pivot-shift testing (RR, 1.06; P = .82; 260 patients in 4 studies), International Knee Documentation Committee final score (RR, 0.87; P = .63; 300 patients in 5 studies), and Lysholm score (SMD, 0.03; P = .89; 204 patients in 4 studies). The incidence of knee effusion was higher in the bioabsorbable screw group (RR, 2.57; P = .04; 421 patients in 4 studies).

Conclusions: There was no significant difference in measurement results of knee joint stability or knee joint function outcome between bioabsorbable and metallic interference screws. Knee joint effusion is more common after ACL reconstruction with bioabsorbable interference screw fixation than with metallic interference screw fixation. More high-methodologic quality randomized controlled trials would be helpful in further meta-analysis.

Level of evidence: Level I, meta-analysis.

PubMed Disclaimer

MeSH terms