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. 2010 Jun 1;20(11):3413-5.
doi: 10.1016/j.bmcl.2010.04.002. Epub 2010 Apr 9.

New dirhodium complex with activity towards colorectal cancer

Raquel F M Frade  1 , Nuno R Candeias, Catarina M M Duarte, Vânia André, M Teresa Duarte, Pedro M P Gois, Carlos A M Afonso
Affiliations

New dirhodium complex with activity towards colorectal cancer

Raquel F M Frade et al. Bioorg Med Chem Lett. .

Abstract

A novel dirhodium complex (Rh(2)(L-PheAla)(2)(OAc)(2) is reported with strong activity towards human colon adenocarcinoma cells. Its effect was not accompanied by generation of reactive oxygen species (ROS) neither by activation of caspase-3.

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