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. 2010 Jul;38(Web Server issue):W14-8.
doi: 10.1093/nar/gkq321. Epub 2010 May 3.

ALTER: program-oriented conversion of DNA and protein alignments

Daniel Glez-Peña  1 , Daniel Gómez-Blanco, Miguel Reboiro-Jato, Florentino Fdez-Riverola, David Posada
Affiliations

ALTER: program-oriented conversion of DNA and protein alignments

Daniel Glez-Peña et al. Nucleic Acids Res. 2010 Jul.

Abstract

ALTER is an open web-based tool to transform between different multiple sequence alignment formats. The originality of ALTER lies in the fact that it focuses on the specifications of mainstream alignment and analysis programs rather than on the conversion among more or less specific formats. In addition, ALTER is capable of identify and remove identical sequences during the transformation process. Besides its user-friendly environment, ALTER allows access to its functionalities in a programmatic way through a Representational State Transfer web service. ALTER's front-end and its API are freely available at http://sing.ei.uvigo.es/ALTER/ and http://sing.ei.uvigo.es/ALTER/api/, respectively.

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Figures

Figure 1.
Figure 1.
Schematic ALTER workflow. The user can select between different input alignment programs and formats, and obtain a MSA specifically formatted for a particular program.
Figure 2.
Figure 2.
Example of a MSA conversion in ALTER. The ‘Info panel’ in the log area shows information related with the process carried out. Help, support for feedback and contact information options are available from the upper left area. Source code and a description of web services are available from the upper right area.
See this image and copyright information in PMC

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