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Comment
. 2010 May 10;207(5):911-3.
doi: 10.1084/jem.20100608. Epub 2010 May 3.

Peripheral T cell lymphoma: new model + new insight

James C Mulloy  1
Affiliations
Comment

Peripheral T cell lymphoma: new model + new insight

James C Mulloy. J Exp Med. .

Abstract

The nonreceptor tyrosine kinase SYK has recently received a good deal of attention as a critical oncogene in various hematologic malignancies. A newly developed model of peripheral T cell lymphoma (PTCL) using the ITK-SYK fusion gene should serve as a powerful tool to dissect the signaling cascades important for SYK-associated malignancy in the context of t(5;9) PTCL.

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