Update on nonneoplastic pulmonary lymphoproliferative disorders and related entities

Abstract

Context: Recent discoveries have expanded the spectrum of nonneoplastic pulmonary lymphoproliferative disorders and have provided new insights into their pathogenesis and treatment.

Objective: To review the thoracic manifestations of immunoglobulin (Ig) G4-related sclerosing disease and summarize current concepts and differential diagnosis of follicular bronchiolitis, lymphocytic interstitial pneumonitis, and nodular lymphoid hyperplasia.

Data sources: Data sources include recent and old articles, cases from the personal files of the author, and cases borrowed with permission from other authors.

Conclusions: Additional studies will be needed to further refine and add to observations in this evolving area of pulmonary pathology.