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Comment
. 2010 May 5;11(5):345-6.
doi: 10.1016/j.cmet.2010.04.012.

Intestinal ecology in the metabolic syndrome

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Intestinal ecology in the metabolic syndrome

Michele Petruzzelli et al. Cell Metab. .
Free article

Abstract

Nutritional and genetic factors alter the intestinal microflora, predisposing individuals toward metabolic syndrome. Gewirtz and coworkers (Vijay-Kumar et al., 2010), employing Toll-like receptor 5 null mice, present evidence for a direct relationship between malfunction of the innate immune system, changes in gut microbiota composition, and development of metabolic syndrome.

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