Re-examination of Rattus norvegicus as an animal model for Aeromonas-associated enteritis in man
- PMID: 2044691
Re-examination of Rattus norvegicus as an animal model for Aeromonas-associated enteritis in man
Abstract
We have developed an oral feeding model for Aeromonas hydrophila enteritis using Rattus norvegicus with clindamycin pretreatment. All animals in the clindamycin group developed a self-limited, loose stool by day four of feeding. Intestinal examination revealed evidence of enteritis. Moreover, antibiotic usage may be a predisposing risk factor to infection.
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