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. 1991 May 15;47(5):452-4.
doi: 10.1007/BF01959941.

Effect of pancreatic secretions upon ileal disaccharidase activities of neonatal miniature pigs

D R Tivey  1 , R J Shulman
Affiliations

Effect of pancreatic secretions upon ileal disaccharidase activities of neonatal miniature pigs

D R Tivey et al. Experientia. .

Abstract

Mechanisms by which pancreatic secretions influence disaccharidase activities in the distal small intestine have been investigated in 1-week-old miniature pigs. Using a combination of biochemical, cytochemical and morphological techniques it has been found that the decrease in lactase specific activity is due solely to a reduction in villus surface area. By contrast, the increased sucrase-isomaltase activities, which occur despite the reduction in villus surface area, are due entirely to increased enzyme expression during enterocyte differentiation.

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