Mastoparan induces hypothermia in mice
- PMID: 2044701
- DOI: 10.1007/BF01959944
Mastoparan induces hypothermia in mice
Abstract
The polypeptide mastoparan, isolated from the venom of the Oriental Hornet, Vespa orientalis, induces hypothermia in white mice 15 minutes after its intraperitoneal injection. The hypothermic effect is induced by mastoparan obtained from different hornet and wasp venoms. The normal murine core temperature is lowered by mastoparan from 38 degrees C to as far as 33 degrees C. This lowering lasts for one hour and is reversible.
Similar articles
-
Hypothermia induced in mice by injection of venom sac extract of hornets (Vespa orientalis, vespinae: hymenoptera).Experientia. 1983 Jan 15;39(1):53-5. doi: 10.1007/BF01960623. Experientia. 1983. PMID: 6825776
-
Structure and biological activities of a new mastoparan isolated from the venom of the hornet Vespa basalis.Biochem J. 1991 Mar 1;274 ( Pt 2)(Pt 2):453-6. doi: 10.1042/bj2740453. Biochem J. 1991. PMID: 2006909 Free PMC article.
-
Isolation and characterization of two new peptides, mastoparan C and crabrolin, from the venom of the European hornet, Vespa crabro.J Biol Chem. 1984 Aug 25;259(16):10106-11. J Biol Chem. 1984. PMID: 6206053
-
Peptide Toxins in Solitary Wasp Venoms.Toxins (Basel). 2016 Apr 18;8(4):114. doi: 10.3390/toxins8040114. Toxins (Basel). 2016. PMID: 27096870 Free PMC article. Review.
-
[Mastoparan as a G protein activator].Tanpakushitsu Kakusan Koso. 2001 Mar;46(4 Suppl):423-8. Tanpakushitsu Kakusan Koso. 2001. PMID: 11268642 Review. Japanese. No abstract available.
References
MeSH terms
Substances
LinkOut - more resources
Medical