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Comment
. 2010 May 7;328(5979):697-8.
doi: 10.1126/science.1190310.

Immunology. Tumor immune evasion

Affiliations
Comment

Immunology. Tumor immune evasion

Carlene L Zindl et al. Science. .
No abstract available

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Figures

Figure 1
Figure 1. Formation of Lymphoid Stroma
CCL21-expressing tumor cells recruit CCR7+ LTi cells, Treg cells, and MDSCs. LTi cells direct the reorganization of local stroma into lymphoid-like structures that support maintenance of Treg cells and MDSCs that lead to immune tolerance of the tumor. TAMs secrete ECM proteins that promote stromal stability.

Comment on

References

    1. Meissner M, et al. Clin Cancer Res. 2005 Apr 1;11:2552. - PubMed
    1. Shevach EM. Nat Med. 2004 Sep;10:900. - PubMed
    1. Shields JD, Kourtis IC, Tomei AA, Swartz MA. Science. 2010;328 - PubMed
    1. Mebius RE, Rennert P, Weissman IL. Immunity. 1997 Oct;7:493. - PubMed
    1. Yoshida H, et al. Int Immunol. 1999 May;11:643. - PubMed