Review
doi: 10.4268/cjcmm20100425.
[Progress in Tripterygium wilfordiiand its bioactive components in the field of pharmacodynamics and pharmacology]
[Article in
Chinese]
Affiliations
- PMID: 20450057
- DOI: 10.4268/cjcmm20100425
Item in Clipboard
Review
[Progress in Tripterygium wilfordiiand its bioactive components in the field of pharmacodynamics and pharmacology]
[Article in
Chinese]
Zhongguo Zhong Yao Za Zhi.
2010 Feb.
Abstract
In the trials of multi-glycoside of Tripterygium wilfordii (GTW) in the field of pharmacodynamics, some clinical characteristics and symptoms, such as proteinuria, hematuria,joint pain, and skin damage, could be improved in the patients with various diseases including proliferative glomerulonephritis, lupus nephritis, rheumatoid arthritis, psoriasis and other immune-related diseases. In this review, it has been also reported to discuss the effects of GTW and Triptolide (T4), which is a bioactive component in GTW on anti-inflammatory, immunosuppression, and protection of epithelial cell in kidney. On the other hand, it is possible to have some beneficial effects on organ transplant rejection, tumor growth and anti-fertility.
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